Hepatomegaly can represent intrinsic liver disease or may be the presenting physical finding of a generalized disorder. It is important to realize that the liver is easily palpated in most children at 1-2 cm below the right costal margin. A normal liver should feel soft and is easily moveable upon inspiration. Hence based on the literature this study has been planned to review various Clinicopathological factors of hepatomegaly in children and study the various cases of hepatomegaly in children. This study is planned in katihar medical college and hospital Katihar in the year June 2004to July 2005. Total 50 children’s with Children with increased liver span were admitted in the study. All patients were subjected to routine investigations like complete hemograme, urine analysis, stool examination, LFT, viral markers and CXR. From the present study it can be concluded that the most common etiological factor was infections, of which viral hepatitis tops the list. Most common symptom is was fever. Most common associated finding was splenomegaly. Majority of cases had mild hepatomegaly and only few cases had massive hepatomegaly due to rare causes like storage disorders.