Objective: To review the current diagnostic modalities for diabetic neuropathy, common long-term complications of diabetes mellitus.

Methods: We performed a MEDLINE using a combination of words (diabetic neuropathy, diagnosis, and treatment) to identify original studies, consensus statements, and reviews published in the last thirty years. Emphasis was on the diagnosis of diabetic distal symmetrical polyneuropathy (the most common form), especially newer modalities.

Results: A plethora of tests are available for the diagnosis of diabetic neuropathy. Some of these are simple and easy to perform in clinical settings while others require sophisticated equipment and expertise to be carried out.

Conclusion: Early screening and diagnosis of diabetic neuropathy, preventive modalities, patient, and physician education remain cardinal factors in reducing this complication and mortality.