Endobronchial mass lesions detected on bronchoscopy can be either benign or malignant. The present study was carried out to assess the profile of endobronchial mass lesions diagnosed by bronchoscopic biopsy. Patients with endobronchial mass lesions diagnosed by bronchoscopic biopsy between June 2014 to December 2015 were included in the study. Out of the 800 flexible bronchoscopies performed during the study period, endobronchial mass lesions were visualised in 81 cases (10.1%). Age ranged from 25 to 86 years with 50 males and 31 females. 67 (83%) lesions were malignant, 8 (10%) lesions were benign while reports of 6 (7%) lesions were inconclusive. Among the malignant lesions, squamous cell carcinoma (76.1%) was reported to be the most common histopathological type. Bronchoscopy with adequate sampling remains the most efficacious diagnostic modality for diagnosing endobronchial mass lesions.