Helicobacter pylori, previously known as Campylobacter pylori, is a gram-negative, microaerophilic bacterium usually found in the stomach. It is also linked to the development of duodenal ulcers and stomach cancer. The study was conducted in the Department of Paediatrics in Sri Krishna Medical College and Hospital. Total 80 patients reported with abdominal pain were enrolled into the study. The childrens who fulfilled Apley's criteria of RAP at least three discrete episodes of abdominal pain of sufficient severity, to interrupt normal daily activities or performance, occurring over a period of three or more months) were enrolled. Helicobacter pylori (HP) infection and Recurrent Abdominal Pain (RAP) are two major childhood challenges presenting a dilemma in diagnosis and treatment. There was no association between HP infection and RAP. There was a significant association between HP infection and epigastric pain, vomiting and IDA in symptomatic children and not in asymptomatic children suggesting that RAP is not an indication for a test-and-treat strategy for HP infection in children.