Background and Aims: Some authors consider heart failure (HF) to be a pandemic now, since nearly 26 million people have been affected by it, globally. Out of these, India alone has around 8-10 million patients. Heart Failure Reversal Therapy (HFRT) combines Herbal Panchakarma therapy with Dietary management. This study was conducted to evaluate the effect of HFRT on VO2peak, 6 Minute Walk Test (6MWT), systolic blood pressure (SBP), and diastolic blood pressure (DBP), BMI, weight, abdominal girth, and heart rate. Setting and Design: This observational study was conducted from January 2015 to December 2017, wherein the data of elderly male patients with HF (NYHA class II and III) with reduced ejection fraction (<40%) who attended Madhavbaug hospital, Khopoli, Maharashtra, India were identified. Materials and Methods: Data of patients who were administered HFRT (60-75 minutes) with minimum 7 sittings over 7 days were considered. Variables were compared between day 1, 7, 30, 60 and day 90 of HFRT. Results: 50 elderly males with HF and EF < 40% were enrolled in the study for analysis. There was significant improvement in VO2peak, from 12.71 ± 2.47 at baseline to 14.89 ± 2.05 at day 90 (p<0.001). 6MWT also showed significant improvement from 339.42 ± 106.85 at day 1 to 432.4 ± 89.27 at day 90 (p<0.001). Also, BMI, abdominal girth, weight showed similar statistically significant improvements. Improvements in SBP, DBP and HR were not statistically significant. Conclusion: From the findings of our study, HFRT has been found to be a potent and viable therapeutic alternative for elderly male patients with HF with reduced ejection fraction.