Diseased liver has many complications which progress to cirrhosis. Cirrhosis is characterized by liver abnormal structure and functions where damage and death of some liver cells form scar tissues and the other living cells multiply to replace the dead cells resulting in regenerative nodules formation within the scar tissues. There are many causes of cirrhosis is caused by many factors like chemicals, viruses, accumulation of toxic metals in the liver and autoimmune liver disease. The major complications of cirrhosis include varices, ascites, hepatic encephalopathy (HE), hepatopulmonary hypertension, hepatocellular carcinoma, hepatorenal syndrome, spontaneous bacterial peritonitis, and coagulation disorders. These can occur secondary to portal hypertension, abnormal synthetic function, or combination of both.