The lateral thoracic artery is a branch of the second part of the axillary artery. The lateral thoracic artery originates from the medial surface of the axillary artery, posterior to the distal part of pectoralis minor. It courses infer o medially along the inferior border of pectoralis minor to the anterior surface of serratus anterior. It anastomoses with the internal thoracic and intercostal arteries as well as with the superior thoracic artery. The study was planned on 20 cadaveric subjects. The axillae from embalmed cadavers allotted for dissection in the Department of Anatomy for duration of 3 years were used for the study. The axillary region was dissected and exposed according to the methods described in Cunningham’s Manual of Practical Anatomy. From the present study the origin of the lateral Thoracic artery was observed; as we found some variations in the origin of the lateral Thoracic artery. It arose from the 2^nd part of the Axillary artery as a common trunk with thoracodorsal artery; as a branch from subscapular artery as double branch of lateral thoracic artery.