Introduction and Aim of Work: Central nervous system (CNS) tumors represent a major public health problem. The epidemiological data in District- Gurugram (Haryana) has been rather incomplete except for some regional reports. There are no available frequency-based data on CNS tumors in our region. The Objective of this Study: was to estimate the frequency of CNS tumors in National Capital of Region-Gurugram. Materials and Methods: The data were collected during the 5-year period from January 2013 to December 2017 from Hospital Based Cancer Registry of Fortis Memorial Research Institute Gurugram, Haryana. Results: During 2013 to 2017, a total of 1279 primary malignant brain and central nervous system tumors were registered. CNS tumors are more common in males than in females. The sex ratio was 498 females to 1,000 males. The most common histological type of primary CNS cancer in both sexes were glioblastoma (30.1%) followed by and glioma (18.8%), astrocytoma (16.7%), oligodendroglioma (7.2%), ependymoma (6.8%), medulloblastoma (5.1%), neuroblastomas (3.4%), primitive neuroectodermal tumor (3.0%), meningioma (2.5%) & others (5.7%) Conclusion: This study provides the largest series of the relative frequency of CNS tumors in NCR region in Gurugram till now and may help to give insight into the epidemiology of CNS tumors.