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VOL. 7, ISSUE 10 (2021)
Association between first trimester blood urea nitrogen and gestational diabetes mellitus in terms of sensitivity analysis
Authors
Nweke Adanne Jane, Abanobi O C, Stanley J Ozims
Abstract
This study evaluated first trimester blood urea nitrogen and risk of gestational diabetes mellitus in pregnant women in Abia State. Three (3) objectives and research questions guided the study which was a descriptive cross-sectional survey. The study population included all first trimester pregnant women accessing antenatal care in three selected Hospital at the time of conducting this study which to talled 224.The entire 224 first trimester pregnant women were selected to participate in the study using the total sampling method. The instruments for data collection consisted of a structured questionnaire and blood samples of the pregnant women. The structured questionnaire elicited information on socio-demographic characteristics of the study participants while the blood samples provided data on blood urea nitrogen levels of the pregnant women. The questionnaires were administered on the study participants by direct delivery and retrieval approach. Blood samples were collected on antenatal clinic visits after due ethical approval was granted. Data analysis was done using descriptive statistics of frequencies, percentages and mean at 0.05 level of significance. Results revealed that higher blood urea nitrogen levels were recorded in women who were older, had higher proportion of parity and gravidity; there is no significant association between marital status and serum blood urea nitrogen levels (P>.05); high levels of blood urea nitrogen were significantly associated with elevated risk of gestational diabetes irrespective of maternal age, gravidity and parity; there are significant associations between high blood urea nitrogen and gestational diabetes mellitus; Statistical tests for interactions between blood urea nitrogen and these interesting factors on outcome were not significant (P>.05). The study concluded that higher concentrations of blood urea nitrogen during the first trimester of pregnancy were positively and independently associated with increased risk of gestational diabetes. Based on the study findings routine monitoring of renal functioning of women as well as their overall endocrine and metabolic changes during pregnancy were recommended. It was also recommended that pregnant women be encouraged to attend antenatal care clinics regularly.
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Pages:10-14
How to cite this article:
Nweke Adanne Jane, Abanobi O C, Stanley J Ozims "Association between first trimester blood urea nitrogen and gestational diabetes mellitus in terms of sensitivity analysis ". International Journal of Medical and Health Research, Vol 7, Issue 10, 2021, Pages 10-14
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