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VOL. 8, ISSUE 1 (2022)
Clinical characteristics, pharmacotherapy and outcome of hospitalized COVID-19 patients in a tertiary care teaching hospital in south India
Authors
A Ruckmani, K R Ilamathi, E Abinaya, R Arunkumar, R Maignana kumar
Abstract
The corona virus disease 2019 (COVID-19) initially identified in Wuhan city of China’s Hubei province, has become an alarming pandemic affecting the world’s population in morbidity and mortality. Though initially the disease manifested as respiratory symptoms, later it involved many other organs and systems and the presentation varied in terms of clinical, laboratory, computerized tomography (CT) findings, and different treatment categories is being tried and used. So this single center retrospective study was undertaken with the objective of characterizing the clinical, diagnostic, treatment and clinical outcome of hospitalized patients diagnosed with COVID-19 in a tertiary hospital. We included the case records of all RTPCR positive COVID-19 patients admitted to the tertiary hospital for which the data were available from admission to discharge irrespective of age, gender and co- morbidities. The data were analyzed using descriptive statistics. Among the 300 patients, 68 COVID-19presented with respiratory symptoms, 88 patients with non-respiratory symptoms and 44 were asymptomatic. We observed elevated ESR in 24%, elevated levels of CRP (43%), LDH (28.76%), D-dimer, (48.2%), fibrinogen (35.3%) and ferritin in 16% of our patients. 72.5% of the patients had findings suggestive of COVID in CT chest.In our study though 26.6% of patients had >3 Neutrophil, Lymphocyte Ratio (NLR) and 28.3% Platelet Lymphocyte Ratio (PLR) more than 180, they did not progress to severe disease. Most common pharmacotherapeutic agents used were Azithromycin, Oseltamivir, Remdesivir, HCQ, Ivermectin, Tocilizumab and Convalescent plasma. Glucocorticoids were used in 54 patients among the 300 patients. Out of 300 patients 285 patients recovered and were discharged. 15 patients were referred to other hospitals upon request. One patient died out of the 285 patients and the mortality was 0.35%. The lower mortality rate could be because of early detection and hospitalization and most patients had mild to moderate disease.
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Pages:6-12
How to cite this article:
A Ruckmani, K R Ilamathi, E Abinaya, R Arunkumar, R Maignana kumar "Clinical characteristics, pharmacotherapy and outcome of hospitalized COVID-19 patients in a tertiary care teaching hospital in south India ". International Journal of Medical and Health Research, Vol 8, Issue 1, 2022, Pages 6-12
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