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VOL. 8, ISSUE 1 (2022)
The prognostic significance of electrocardiography findings in patients with coronavirus disease 2019: A retrospective study at tertiary care hospital from north India
Authors
Premshanker Singh, Ajay Misra, M S Siddique, Pragnesh Laxman Bhai
Abstract
There is growing evidence of cardiac injury in COVID-19. Our purpose was to assess the prognostic value of serial electrocardiograms in COVID-19 patients. Coronavirus disease 2019 (COVID-19) has reached a pandemic level. Cardiac injury is not uncommon among COVID-19 patients. We attempted to describe the electrocardiographic characteristics and to identify the prognostic significance of electrocardiography (ECG) findings of patients with COVID-19.Consecutive patients with laboratory-confirmed COVID-19 and definite in-hospital outcome were retrospectively included. Demographic characteristics and clinical data were extracted from medical record. Initial ECGs at admission and thereafter during hospitalization were reviewed. A point-based scoring system of abnormal ECG findings was formed, in which 1 point each was assigned for the presence of axis deviation, arrhythmias, atrioventricular block, conduction tissue disease, QTc interval prolongation, pathological Q wave, ST-segment change, and T-wave changes. The association between abnormal ECG scores and in-hospital mortality was assessed in multivariable Cox regression models. Total of 612 patients were included. T-wave change (31.7%), QTc interval prolongation (30.1%), and arrhythmias (16.3%) were three most common found ECG abnormalities. 60 (9.80%) patients died during hospitalization. Abnormal ECG scores were significantly higher among non-survivors (median 2 points vs 1 point, p < 0.001). The risk of in-hospital death increased by a factor of 1.478 (HR 1.478, 95% CI 1.131–1.933, p = 0.004) after adjusted by age, comorbidities, cardiac injury and treatment. ECG abnormality was associated with higher risk of death.ECG abnormality was common in patients admitted for COVID-19 and was associated with adverse in-hospital outcome. In-hospital mortality risk increased with increasing abnormal ECG scores.
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Pages:54-60
How to cite this article:
Premshanker Singh, Ajay Misra, M S Siddique, Pragnesh Laxman Bhai "The prognostic significance of electrocardiography findings in patients with coronavirus disease 2019: A retrospective study at tertiary care hospital from north India ". International Journal of Medical and Health Research, Vol 8, Issue 1, 2022, Pages 54-60
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